Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones.

Sooksawate, T

Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones. [electronic resource] - Neuropharmacology Sep 1998 - 1103-10 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0028-3908

10.1016/s0028-3908(98)00113-0 doi


Animals
Cholesterol--metabolism
Dose-Response Relationship, Drug
Hippocampus--cytology
Liposomes
Membrane Potentials--drug effects
Neurons--drug effects
Patch-Clamp Techniques
Pregnanediones--pharmacology
Pregnanolone--pharmacology
Propofol--pharmacology
Rats
Rats, Wistar
Receptors, GABA-A--drug effects
Steroids--pharmacology
Synapses--drug effects
Synaptic Membranes--metabolism
gamma-Aminobutyric Acid--pharmacology