Anti-C5a monoclonal antibody reduces cardiopulmonary bypass and cardioplegia-induced coronary endothelial dysfunction.

Tofukuji, M

Anti-C5a monoclonal antibody reduces cardiopulmonary bypass and cardioplegia-induced coronary endothelial dysfunction. [electronic resource] - The Journal of thoracic and cardiovascular surgery Dec 1998 - 1060-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-5223

10.1016/S0022-5223(98)70059-5 doi


Animals
Antibodies, Monoclonal--therapeutic use
Cardiopulmonary Bypass--adverse effects
Chemotaxis, Leukocyte--drug effects
Complement C5a--immunology
Coronary Vessels--drug effects
Endothelium, Vascular--drug effects
Female
Heart Arrest, Induced--adverse effects
Hemodynamics--drug effects
Male
Mice
Mice, Inbred BALB C
Myocardial Reperfusion Injury--enzymology
Neutrophils--drug effects
Nitric Oxide Synthase--metabolism
Nitric Oxide Synthase Type II
Nitric Oxide Synthase Type III
Peroxidase--metabolism
Swine