A phase II "window" study of topotecan in untreated patients with high risk adult acute lymphoblastic leukemia.

Gore, S D

A phase II "window" study of topotecan in untreated patients with high risk adult acute lymphoblastic leukemia. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Nov 1998 - 2677-89 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase II; Journal Article; Research Support, U.S. Gov't, P.H.S.

1078-0432


Adult
Aged
Antineoplastic Agents--adverse effects
Bone Marrow--drug effects
DNA Topoisomerases, Type I--metabolism
Female
Humans
Leukocyte Count--drug effects
Male
Middle Aged
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
Risk Factors
Topoisomerase I Inhibitors
Topotecan--adverse effects
Treatment Outcome