Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide.
Bruneau, J M
Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide. [electronic resource] - The Biochemical journal Dec 1998 - 299-303 p. digital
Publication Type: Journal Article
0264-6021
10.1042/bj3360299 doi
Aniline Compounds--metabolism
Binding Sites
Binding, Competitive
Cell Division--drug effects
Cell Membrane--drug effects
Crotonates
Dihydroorotate Dehydrogenase
Humans
Hydroxybutyrates--metabolism
Lymphoma--enzymology
Nitriles
Oxidoreductases--antagonists & inhibitors
Oxidoreductases Acting on CH-CH Group Donors
Spleen--enzymology
Toluidines
Tumor Cells, Cultured
Uridine--metabolism
Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide. [electronic resource] - The Biochemical journal Dec 1998 - 299-303 p. digital
Publication Type: Journal Article
0264-6021
10.1042/bj3360299 doi
Aniline Compounds--metabolism
Binding Sites
Binding, Competitive
Cell Division--drug effects
Cell Membrane--drug effects
Crotonates
Dihydroorotate Dehydrogenase
Humans
Hydroxybutyrates--metabolism
Lymphoma--enzymology
Nitriles
Oxidoreductases--antagonists & inhibitors
Oxidoreductases Acting on CH-CH Group Donors
Spleen--enzymology
Toluidines
Tumor Cells, Cultured
Uridine--metabolism