Randomized, double-blind, placebo-controlled study of carvedilol on the prevention of nitrate tolerance in patients with chronic heart failure.

Watanabe, H

Randomized, double-blind, placebo-controlled study of carvedilol on the prevention of nitrate tolerance in patients with chronic heart failure. [electronic resource] - Journal of the American College of Cardiology Nov 1998 - 1194-200 p. digital

Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial

0735-1097

10.1016/s0735-1097(98)00392-1 doi


Adrenergic Antagonists--therapeutic use
Aged
Blood Flow Velocity--drug effects
Blood Platelets--metabolism
Blood Pressure--drug effects
Carbazoles--therapeutic use
Carvedilol
Chronic Disease
Cyclic GMP--biosynthesis
Double-Blind Method
Doxazosin--therapeutic use
Drug Hypersensitivity--blood
Drug Therapy, Combination
Female
Follow-Up Studies
Forearm--blood supply
Heart Failure--blood
Heart Rate--drug effects
Humans
Male
Metoprolol--therapeutic use
Middle Aged
Nitroglycerin--adverse effects
Propanolamines--therapeutic use
Vasodilator Agents--adverse effects