The effect of human beta2-microglobulin on major histocompatibility complex I peptide loading and the engineering of a high affinity variant. Implications for peptide-based vaccines.

Shields, M J

The effect of human beta2-microglobulin on major histocompatibility complex I peptide loading and the engineering of a high affinity variant. Implications for peptide-based vaccines. [electronic resource] - The Journal of biological chemistry Oct 1998 - 28010-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.273.43.28010 doi


Antigen Presentation
Drug Design
Genetic Variation
HLA-A Antigens--metabolism
Humans
Mutagenesis, Site-Directed
Peptides--metabolism
Protein Binding
Protein Engineering
T-Lymphocytes, Cytotoxic
Vaccines--immunology
beta 2-Microglobulin--genetics