IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production.
Grohmann, U
IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production. [electronic resource] - Immunity Sep 1998 - 315-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1074-7613
10.1016/s1074-7613(00)80614-7 doi
Animals
Cell Nucleus--metabolism
Cells, Cultured
DNA--metabolism
DNA-Binding Proteins--drug effects
Dendritic Cells--drug effects
Histocompatibility Antigens Class II--biosynthesis
Interleukin-12--metabolism
Lipopolysaccharides--pharmacology
Male
Mice
Mice, Inbred DBA
NF-kappa B--drug effects
NF-kappa B p50 Subunit
RNA, Messenger--biosynthesis
Receptors, Interleukin--genetics
Receptors, Interleukin-12
STAT3 Transcription Factor
STAT4 Transcription Factor
Trans-Activators--drug effects
Transcription Factors--drug effects
IL-12 acts directly on DC to promote nuclear localization of NF-kappaB and primes DC for IL-12 production. [electronic resource] - Immunity Sep 1998 - 315-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1074-7613
10.1016/s1074-7613(00)80614-7 doi
Animals
Cell Nucleus--metabolism
Cells, Cultured
DNA--metabolism
DNA-Binding Proteins--drug effects
Dendritic Cells--drug effects
Histocompatibility Antigens Class II--biosynthesis
Interleukin-12--metabolism
Lipopolysaccharides--pharmacology
Male
Mice
Mice, Inbred DBA
NF-kappa B--drug effects
NF-kappa B p50 Subunit
RNA, Messenger--biosynthesis
Receptors, Interleukin--genetics
Receptors, Interleukin-12
STAT3 Transcription Factor
STAT4 Transcription Factor
Trans-Activators--drug effects
Transcription Factors--drug effects