Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.

Sarkaria, J N

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. [electronic resource] - Cancer research Oct 1998 - 4375-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0008-5472


Adenocarcinoma
Androstadienes--pharmacology
Ataxia Telangiectasia Mutated Proteins
Cell Cycle--drug effects
Cell Cycle Proteins
DNA, Neoplasm--biosynthesis
DNA-Activated Protein Kinase
DNA-Binding Proteins
Enzyme Inhibitors--pharmacology
G2 Phase
Humans
Kinetics
Lung Neoplasms
Nuclear Proteins
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proteins--antagonists & inhibitors
Radiation-Sensitizing Agents--pharmacology
S Phase
Tumor Cells, Cultured
Tumor Suppressor Proteins
Wortmannin