In vivo and in vitro activities of the gp130-stimulating designer cytokine Hyper-IL-6.

Peters, M

In vivo and in vitro activities of the gp130-stimulating designer cytokine Hyper-IL-6. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Oct 1998 - 3575-81 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0022-1767


Acute-Phase Reaction--blood
Animals
Antigens, CD--metabolism
Cell Line
Cytokine Receptor gp130
Drug Design
Gene Expression--drug effects
Haptoglobins--genetics
Humans
Injections, Intraperitoneal
Interleukin-6--administration & dosage
Iodine Radioisotopes--metabolism
Liver--drug effects
Membrane Glycoproteins--metabolism
Mice
Protein Binding
RNA, Messenger--biosynthesis
Receptors, Interleukin--administration & dosage
Receptors, Interleukin-6
Recombinant Fusion Proteins--administration & dosage
Signal Transduction--drug effects
Time Factors
Tumor Cells, Cultured