Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.

De Rosa, M

Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues. [electronic resource] - Journal of medicinal chemistry Aug 1998 - 3232-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm980027h doi


4-Butyrolactone--analogs & derivatives
Animals
Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis
Bee Venoms
Carrageenan
Cell Line
Cytosol--enzymology
Drug Design
Edema--chemically induced
Elapid Venoms
Enzyme Inhibitors--chemical synthesis
Female
Humans
Kinetics
Mice
Molecular Structure
Pancreas--enzymology
Phospholipases A--antagonists & inhibitors
Phospholipases A2
Pyrans--pharmacology
Structure-Activity Relationship
Swine
Synovial Membrane--enzymology
Terpenes--chemical synthesis