Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.

Hresko, R C

Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. [electronic resource] - The Journal of biological chemistry Aug 1998 - 20658-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.273.32.20658 doi


3T3 Cells
Adenosine Triphosphate--metabolism
Adipocytes--drug effects
Animals
Cell Fractionation
Deoxyglucose--pharmacokinetics
Glucosamine--pharmacology
Glucose--metabolism
Glucose Transporter Type 1
Glucose Transporter Type 4
Inosine--pharmacology
Insulin Receptor Substrate Proteins
Insulin Resistance--physiology
Mice
Monosaccharide Transport Proteins--metabolism
Muscle Proteins
Phosphatidylinositol 3-Kinases--metabolism
Phosphoproteins--metabolism
Phosphorylation
Phosphotyrosine
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Receptor Protein-Tyrosine Kinases--metabolism
Receptor, Insulin--metabolism
Sodium Azide--pharmacology