Transforming growth factor-beta-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-XL downregulation.

Saltzman, A

Transforming growth factor-beta-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-XL downregulation. [electronic resource] - Experimental cell research Jul 1998 - 244-54 p. digital

Publication Type: Journal Article

0014-4827

10.1006/excr.1998.4096 doi


Amino Acid Chloromethyl Ketones--pharmacology
Annexin A5--metabolism
Apoptosis--physiology
Apoptosis Regulatory Proteins
B-Lymphocytes--cytology
Burkitt Lymphoma
Caspase 3
Caspases
Cell Cycle
Cysteine Endopeptidases--metabolism
Cysteine Proteinase Inhibitors--pharmacology
DNA--analysis
Enzyme Activation
Gene Expression Regulation, Neoplastic
Humans
I-kappa B Proteins
Membrane Proteins
Mitochondrial Proteins
Proteins--genetics
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-bcl-2--analysis
RNA, Messenger--analysis
Transforming Growth Factor beta--pharmacology
Tumor Cells, Cultured
X-Linked Inhibitor of Apoptosis Protein
bcl-X Protein
fas Receptor--genetics