In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase.

Panek, R L

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 1998 - 569-77 p. digital

Publication Type: Journal Article

0022-3565


3T3 Cells
Animals
Fibroblast Growth Factors--pharmacology
Humans
In Vitro Techniques
Mice
Neovascularization, Physiologic--drug effects
Phosphorylation
Protein-Tyrosine Kinases--metabolism
Pyrimidines--pharmacology
Rats
Receptor Protein-Tyrosine Kinases--antagonists & inhibitors
Receptor, Fibroblast Growth Factor, Type 1
Receptors, Fibroblast Growth Factor--antagonists & inhibitors
Urea--analogs & derivatives