Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors.

Sarukhan, A

Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors. [electronic resource] - Immunity May 1998 - 563-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1074-7613

10.1016/s1074-7613(00)80561-0 doi


Alleles
Animals
Autoimmunity--genetics
CD4-Positive T-Lymphocytes--immunology
Diabetes Mellitus, Type 1--etiology
Hemagglutinin Glycoproteins, Influenza Virus--immunology
Insulin--genetics
Mice
Mice, Inbred BALB C
Mice, Transgenic
Pancreas--immunology
Promoter Regions, Genetic
Rats
Receptors, Antigen, T-Cell, alpha-beta--biosynthesis
Self Tolerance--genetics