Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study.

Sun, Y

Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study. [electronic resource] - Gene therapy Apr 1998 - 481-90 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

0969-7128

10.1038/sj.gt.3300619 doi


Adult
Biolistics
Cancer Vaccines
Female
Gene Transfer Techniques
Genetic Therapy--methods
Humans
Hypersensitivity, Delayed
Immunohistochemistry
Interleukin-10--metabolism
Interleukin-12--genetics
Killer Cells, Natural--immunology
Male
Melanoma--immunology
Middle Aged
Polymerase Chain Reaction
T-Lymphocytes--immunology
Transforming Growth Factor beta--metabolism
Tumor Cells, Cultured