Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects.

Hol, F A

Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects. [electronic resource] - Clinical genetics Feb 1998 - 119-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-9163

10.1111/j.1399-0004.1998.tb02658.x doi


Aminohydrolases--genetics
Base Sequence
DNA, Complementary
Female
Formate-Tetrahydrofolate Ligase--genetics
Humans
Male
Methenyltetrahydrofolate Cyclohydrolase
Methylenetetrahydrofolate Dehydrogenase (NADP)--genetics
Molecular Sequence Data
Neural Tube Defects--enzymology
Pedigree
Polymorphism, Single-Stranded Conformational