Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes.

Barron, L G

Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes. [electronic resource] - Human gene therapy Feb 1998 - 315-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1043-0342

10.1089/hum.1998.9.3-315 doi


Animals
Cations
Cholesterol--immunology
Complement C3--immunology
Complement C3a--immunology
Complement Inactivator Proteins--pharmacology
DNA--immunology
Drug Carriers
Elapid Venoms--pharmacology
Fatty Acids, Monounsaturated--immunology
Female
Gene Expression
Gene Transfer Techniques
Humans
Liposomes--immunology
Luciferases--genetics
Lung--metabolism
Mice
Mice, Inbred ICR
Quaternary Ammonium Compounds--immunology