Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production.

Kuperman, D

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. [electronic resource] - The Journal of experimental medicine Mar 1998 - 939-48 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1007

10.1084/jem.187.6.939 doi


Animals
Antigens--immunology
Bronchial Hyperreactivity--etiology
Eosinophilia--etiology
Female
Immunoglobulin E--biosynthesis
Immunoglobulin G--biosynthesis
Interleukin-4--biosynthesis
Interleukin-5--biosynthesis
Male
Mice
Mice, Inbred BALB C
Mucus--physiology
Ovalbumin--immunology
STAT6 Transcription Factor
Trans-Activators--deficiency
Vascular Cell Adhesion Molecule-1--analysis