Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes.

Pawelek, P D

Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes. [electronic resource] - Biochemistry Jan 1998 - 1109-15 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0006-2960

10.1021/bi971906t doi


Adenosine Diphosphate--pharmacology
Aminohydrolases--drug effects
Bacterial Proteins--metabolism
Formate-Tetrahydrofolate Ligase--drug effects
Humans
Kinetics
Leucovorin--analogs & derivatives
Methylenetetrahydrofolate Dehydrogenase (NADP)--drug effects
Mitochondria--enzymology
Models, Chemical
Multienzyme Complexes--drug effects
NAD--metabolism
NADP--metabolism
Photobacterium--enzymology
Tetrahydrofolates--metabolism