Integrated amplification and detection of the C677T point mutation in the methylenetetrahydrofolate reductase gene by fluorescence resonance energy transfer and probe melting curves.

Bernard, P S

Integrated amplification and detection of the C677T point mutation in the methylenetetrahydrofolate reductase gene by fluorescence resonance energy transfer and probe melting curves. [electronic resource] - Analytical biochemistry Jan 1998 - 101-7 p. digital

Publication Type: Journal Article

0003-2697

10.1006/abio.1997.2427 doi


Alleles
DNA--chemistry
Energy Transfer
Fluorescent Dyes
Gene Frequency
Genes
Genotype
Heterozygote
Homozygote
Hot Temperature
Methylenetetrahydrofolate Reductase (NADPH2)
Nucleic Acid Denaturation
Nucleic Acid Heteroduplexes--chemistry
Oxidoreductases Acting on CH-NH Group Donors--genetics
Point Mutation--genetics
Polymerase Chain Reaction
Spectrometry, Fluorescence