Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels.

Franqueza, L

Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels. [electronic resource] - Circulation research Dec 1997 - 1053-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0009-7330

10.1161/01.res.81.6.1053 doi


Amino Acid Sequence
Anesthetics, Local--pharmacology
Binding Sites
Bupivacaine--pharmacology
Dose-Response Relationship, Drug
Humans
Kv1.5 Potassium Channel
Molecular Sequence Data
Mutagenesis, Site-Directed
Potassium Channels--drug effects
Potassium Channels, Voltage-Gated
Stereoisomerism
Structure-Activity Relationship
Tetraethylammonium Compounds--metabolism
Time Factors