Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.

Hum, M C

Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro. [electronic resource] - Pharmacotherapy - 1260-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0277-0008


Antimetabolites, Antineoplastic--metabolism
B-Lymphocytes--metabolism
Chromatography, High Pressure Liquid
Humans
Methotrexate--metabolism
Polyglutamic Acid--metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Tumor Cells, Cultured