Determination of hemoglobin adducts following oral administration of 1-nitropyrene to rats using gas chromatography-tandem mass spectrometry.

van Bekkum, Y M

Determination of hemoglobin adducts following oral administration of 1-nitropyrene to rats using gas chromatography-tandem mass spectrometry. [electronic resource] - Journal of chromatography. B, Biomedical sciences and applications Nov 1997 - 19-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1387-2273

10.1016/s0378-4347(97)00356-3 doi


Administration, Oral
Animals
Biomarkers--blood
Carcinogens, Environmental--analysis
Gas Chromatography-Mass Spectrometry
Hemoglobins--metabolism
Hydrolysis
Male
Pyrenes--analysis
Rats
Rats, Sprague-Dawley
Reproducibility of Results
Sensitivity and Specificity
Time Factors