Cytokine-induced nitric oxide inhibits bone resorption by inducing apoptosis of osteoclast progenitors and suppressing osteoclast activity.
van't Hof, R J
Cytokine-induced nitric oxide inhibits bone resorption by inducing apoptosis of osteoclast progenitors and suppressing osteoclast activity. [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Nov 1997 - 1797-804 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0884-0431
10.1359/jbmr.1997.12.11.1797 doi
Animals
Apoptosis--drug effects
Bone Marrow Cells--drug effects
Bone Resorption--chemically induced
Coculture Techniques
Enzyme Induction--drug effects
Interferon-gamma--pharmacology
Interleukin-1
Mice
Mice, Inbred BALB C
Nitric Oxide--biosynthesis
Nitric Oxide Synthase--antagonists & inhibitors
Osteoblasts--drug effects
Osteoclasts--drug effects
Stem Cells--drug effects
Tumor Necrosis Factor-alpha
omega-N-Methylarginine--pharmacology
Cytokine-induced nitric oxide inhibits bone resorption by inducing apoptosis of osteoclast progenitors and suppressing osteoclast activity. [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Nov 1997 - 1797-804 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0884-0431
10.1359/jbmr.1997.12.11.1797 doi
Animals
Apoptosis--drug effects
Bone Marrow Cells--drug effects
Bone Resorption--chemically induced
Coculture Techniques
Enzyme Induction--drug effects
Interferon-gamma--pharmacology
Interleukin-1
Mice
Mice, Inbred BALB C
Nitric Oxide--biosynthesis
Nitric Oxide Synthase--antagonists & inhibitors
Osteoblasts--drug effects
Osteoclasts--drug effects
Stem Cells--drug effects
Tumor Necrosis Factor-alpha
omega-N-Methylarginine--pharmacology