Gly166 in the NK1 receptor regulates tachykinin selectivity and receptor conformation.

Ciucci, A

Gly166 in the NK1 receptor regulates tachykinin selectivity and receptor conformation. [electronic resource] - FEBS letters Oct 1997 - 335-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-5793

10.1016/s0014-5793(97)01236-2 doi


Amino Acid Substitution
Animals
Binding Sites
CHO Cells
COS Cells
Cricetinae
Cysteine
Dithiothreitol--pharmacology
Ethylmaleimide--pharmacology
Glycine
Humans
Kinetics
Mutagenesis, Site-Directed
Neurokinin A--metabolism
Neurokinin B--metabolism
Protein Conformation
Rats
Receptors, Neurokinin-1--chemistry
Receptors, Tachykinin
Recombinant Proteins--chemistry
Substance P--metabolism