Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation.
Sall, D J
Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation. [electronic resource] - Journal of medicinal chemistry Oct 1997 - 3489-93 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm9704107 doi
Animals
Binding Sites
Crystallography, X-Ray
Humans
Serine Proteinase Inhibitors--chemistry
Structure-Activity Relationship
Thiophenes--chemistry
Thrombin--antagonists & inhibitors
Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation. [electronic resource] - Journal of medicinal chemistry Oct 1997 - 3489-93 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm9704107 doi
Animals
Binding Sites
Crystallography, X-Ray
Humans
Serine Proteinase Inhibitors--chemistry
Structure-Activity Relationship
Thiophenes--chemistry
Thrombin--antagonists & inhibitors