Phosphodiesterase inhibition overcomes pulmonary vasomotor dysfunction in acute lung injury.

Sheridan, B C

Phosphodiesterase inhibition overcomes pulmonary vasomotor dysfunction in acute lung injury. [electronic resource] - The Journal of surgical research Aug 1997 - 145-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-4804

10.1006/jsre.1997.5139 doi


1-Methyl-3-isobutylxanthine--pharmacology
Animals
Calcimycin--pharmacology
Cyclic GMP--physiology
Endothelium, Vascular--physiology
Endotoxins--toxicity
Male
Muscle, Smooth, Vascular--physiology
Nitroprusside--pharmacology
Phosphodiesterase Inhibitors--pharmacology
Pulmonary Artery--drug effects
Rats
Rats, Sprague-Dawley
Respiratory Distress Syndrome--drug therapy
Vasodilation--drug effects