Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain.

MacPhee, I J

Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain. [electronic resource] - The Journal of biological chemistry Sep 1997 - 23547-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.272.38.23547 doi


Animals
Brain-Derived Neurotrophic Factor--metabolism
PC12 Cells
Phosphorylation
Protein Binding
Rats
Receptor Protein-Tyrosine Kinases--metabolism
Receptor, Nerve Growth Factor
Receptor, trkA--metabolism
Receptors, Nerve Growth Factor--metabolism
Serine--metabolism
Signal Transduction