Ethanol upregulates the expression of p21 WAF1/CIP1 and prolongs G1 transition via a p53-independent pathway in human epithelial cells.

Guo, W

Ethanol upregulates the expression of p21 WAF1/CIP1 and prolongs G1 transition via a p53-independent pathway in human epithelial cells. [electronic resource] - Oncogene Sep 1997 - 1143-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0950-9232

10.1038/sj.onc.1201287 doi


CDC2-CDC28 Kinases
Cell Cycle--drug effects
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinases--metabolism
Cyclins--genetics
Epithelial Cells
Ethanol--pharmacology
G1 Phase--drug effects
Humans
Intracellular Signaling Peptides and Proteins
Keratinocytes--cytology
Promoter Regions, Genetic
Protein Serine-Threonine Kinases--metabolism
Proteins--metabolism
RNA, Messenger--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--physiology
Up-Regulation--drug effects
GADD45 Proteins