Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists.
Sall, D J
Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists. [electronic resource] - Journal of medicinal chemistry Aug 1997 - 2843-57 p. digital
Publication Type: Comparative Study; Journal Article
0022-2623
10.1021/jm970020k doi
Arginine
Benzamidines--chemical synthesis
Enzyme-Linked Immunosorbent Assay
Fibrinogen--metabolism
Humans
Indicators and Reagents
Models, Molecular
Molecular Conformation
Molecular Structure
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--chemical synthesis
Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors
Structure-Activity Relationship
Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists. [electronic resource] - Journal of medicinal chemistry Aug 1997 - 2843-57 p. digital
Publication Type: Comparative Study; Journal Article
0022-2623
10.1021/jm970020k doi
Arginine
Benzamidines--chemical synthesis
Enzyme-Linked Immunosorbent Assay
Fibrinogen--metabolism
Humans
Indicators and Reagents
Models, Molecular
Molecular Conformation
Molecular Structure
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--chemical synthesis
Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors
Structure-Activity Relationship