Tissue specific toxicities of the anticancer drug 6-thioguanine is dependent on the Hprt status in transgenic mice.

Aubrecht, J

Tissue specific toxicities of the anticancer drug 6-thioguanine is dependent on the Hprt status in transgenic mice. [electronic resource] - The Journal of pharmacology and experimental therapeutics Aug 1997 - 1102-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3565


Adenine--analogs & derivatives
Adenine Phosphoribosyltransferase--antagonists & inhibitors
Animals
Antineoplastic Agents--administration & dosage
Enzyme Inhibitors--pharmacology
Female
Hypoxanthine Phosphoribosyltransferase--genetics
Mice
Mice, Transgenic
Organ Specificity
Thioguanine--administration & dosage