The replacement of Lys620 by serine desensitizes Escherichia coli phosphoenolpyruvate carboxylase to the effects of the feedback inhibitors L-aspartate and L-malate.

Yano, M

The replacement of Lys620 by serine desensitizes Escherichia coli phosphoenolpyruvate carboxylase to the effects of the feedback inhibitors L-aspartate and L-malate. [electronic resource] - European journal of biochemistry Jul 1997 - 74-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2956

10.1111/j.1432-1033.1997.t01-1-00074.x doi


Amino Acid Sequence
Aspartic Acid--pharmacology
Enzyme Inhibitors--pharmacology
Escherichia coli--enzymology
Feedback
Kinetics
Malates--pharmacology
Molecular Sequence Data
Mutagenesis, Site-Directed
Phosphoenolpyruvate Carboxylase--antagonists & inhibitors
Structure-Activity Relationship