Induction of interleukin-2 unresponsiveness and down-regulation of the JAK-STAT system upon activation through the T cell receptor.

Miyatake, S

Induction of interleukin-2 unresponsiveness and down-regulation of the JAK-STAT system upon activation through the T cell receptor. [electronic resource] - European journal of immunology Jul 1997 - 1816-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2980

10.1002/eji.1830270733 doi


Animals
Cell Division--genetics
Clone Cells
Cyclin D3
Cyclins--genetics
DNA-Binding Proteins--metabolism
Down-Regulation--immunology
Gene Expression Regulation--immunology
Immune Tolerance
Interleukin-2--physiology
Janus Kinase 3
Lymphocyte Activation
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Transgenic
Milk Proteins
Protein-Tyrosine Kinases--metabolism
Proto-Oncogene Proteins c-bcl-2--genetics
Receptors, Antigen, T-Cell--physiology
STAT5 Transcription Factor
Signal Transduction--immunology
T-Lymphocytes--cytology
Trans-Activators--metabolism