Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes.

Nomura, A

Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes. [electronic resource] - The Journal of pharmacy and pharmacology Mar 1997 - 257-62 p. digital

Publication Type: Journal Article

0022-3573

10.1111/j.2042-7158.1997.tb06791.x doi


Animals
Antibodies--immunology
Aryl Hydrocarbon Hydroxylases
Chlorpheniramine--pharmacokinetics
Cytochrome P-450 CYP1A1--immunology
Cytochrome P-450 CYP2B1--immunology
Cytochrome P-450 CYP2E1--immunology
Cytochrome P-450 Enzyme System--immunology
Cytochrome P450 Family 2
Histamine H1 Antagonists--pharmacokinetics
In Vitro Techniques
Isoenzymes--immunology
Male
Methylcholanthrene--pharmacology
Microsomes, Liver--drug effects
Phenobarbital--pharmacology
Rats
Rats, Wistar
Stereoisomerism
Steroid 16-alpha-Hydroxylase
Steroid Hydroxylases--immunology