Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15.

Iavarone, A

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15. [electronic resource] - Nature May 1997 - 417-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0028-0836

10.1038/387417a0 doi


Carrier Proteins--metabolism
Cell Cycle--drug effects
Cell Cycle Proteins--antagonists & inhibitors
Cell Line
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinases--antagonists & inhibitors
Cyclins--metabolism
Down-Regulation
Enzyme Activation
Mutagenesis
Phosphoprotein Phosphatases--antagonists & inhibitors
Phosphorylation
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins
Retinoblastoma Protein--metabolism
Transforming Growth Factor beta--pharmacology
Tumor Cells, Cultured
cdc25 Phosphatases