Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation.

Cook, J J

Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation. [electronic resource] - The Journal of pharmacology and experimental therapeutics May 1997 - 677-89 p. digital

Publication Type: Journal Article

0022-3565


Adenosine Diphosphate--antagonists & inhibitors
Animals
Azepines--administration & dosage
Bleeding Time
Disease Models, Animal
Dogs
Drug Administration Routes
Fibrinolytic Agents--administration & dosage
Macaca mulatta
Pan troglodytes
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--administration & dosage
Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors
Sulfonamides--administration & dosage
Thrombosis--prevention & control