Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism.
Lewis, D F
Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Apr 1997 - 319-39 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0049-8254
10.1080/004982597240497 doi
Alleles
Amino Acid Sequence
Bacterial Proteins
Cytochrome P-450 CYP2D6--chemistry
Cytochrome P-450 Enzyme System--chemistry
Isoenzymes--chemistry
Mixed Function Oxygenases--chemistry
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
NADPH-Ferrihemoprotein Reductase
Ondansetron--metabolism
Polymorphism, Genetic
Sequence Homology, Amino Acid
Serotonin Antagonists--metabolism
Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Apr 1997 - 319-39 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0049-8254
10.1080/004982597240497 doi
Alleles
Amino Acid Sequence
Bacterial Proteins
Cytochrome P-450 CYP2D6--chemistry
Cytochrome P-450 Enzyme System--chemistry
Isoenzymes--chemistry
Mixed Function Oxygenases--chemistry
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
NADPH-Ferrihemoprotein Reductase
Ondansetron--metabolism
Polymorphism, Genetic
Sequence Homology, Amino Acid
Serotonin Antagonists--metabolism