Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding.

Gachhui, R

Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding. [electronic resource] - Biochemistry Apr 1997 - 5097-103 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-2960

10.1021/bi970331x doi


Alanine
Amino Acid Sequence
Animals
Antioxidants--metabolism
Arginine--metabolism
Biopterins--analogs & derivatives
Cattle
Chromatography, Gel
Glutamic Acid--metabolism
Heme--metabolism
Humans
Mice
Molecular Sequence Data
Mutagenesis, Site-Directed
Nitric Oxide Synthase--genetics
Oxygenases--genetics
Rats
Structure-Activity Relationship