Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

Wang, X J

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 1997 - 2386-91 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.94.6.2386 doi


Amino Acid Sequence
Animals
Animals, Newborn
Cell Division--drug effects
Cells, Cultured
Epidermis--drug effects
Epitopes--chemistry
Female
Genes, myc
Humans
Hypertrophy
Keratinocytes--cytology
Keratosis--genetics
Male
Mice
Mice, Inbred ICR
Mice, Inbred Strains
Mice, Transgenic
Mitotic Index
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins c-myc--biosynthesis
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta--biosynthesis
Skin--pathology
Skin Aging
Skin Physiological Phenomena
Transforming Growth Factor beta--pharmacology