Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway.

Furuya, K N

Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway. [electronic resource] - The Journal of biological chemistry Apr 1997 - 11518-25 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.272.17.11518 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis
Amino Acid Sequence
Animals
Bromocriptine--pharmacology
Dopamine Agonists--pharmacology
Dopamine Antagonists--pharmacology
Dose-Response Relationship, Drug
Drug Resistance, Multiple--genetics
GTP-Binding Proteins--metabolism
Genes, MDR
Molecular Sequence Data
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-raf
Rats
Receptors, Dopamine D1--metabolism
Receptors, Dopamine D2--metabolism
Signal Transduction
Transcription, Genetic
Tumor Cells, Cultured
Up-Regulation