1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a substrate of cytochrome P450 2D6: allosteric effects of NADPH-cytochrome P450 reductase.

Modi, S

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a substrate of cytochrome P450 2D6: allosteric effects of NADPH-cytochrome P450 reductase. [electronic resource] - Biochemistry Apr 1997 - 4461-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2960

10.1021/bi962633p doi


1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine--chemistry
Allosteric Regulation
Binding Sites
Codeine--metabolism
Cytochrome P-450 CYP2D6--drug effects
Ethanolamines--metabolism
Humans
Models, Molecular
NADH, NADPH Oxidoreductases--metabolism
NADPH-Ferrihemoprotein Reductase
Structure-Activity Relationship
Substrate Specificity