Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria.

Castilho, R F

Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria. [electronic resource] - Free radical biology & medicine Mar 1995 - 479-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0891-5849

10.1016/0891-5849(94)00166-h doi


4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid--pharmacology
Anaerobiosis
Animals
Calcium--metabolism
Catalase--pharmacology
Cross-Linking Reagents--pharmacology
Free Radicals--metabolism
In Vitro Techniques
Intracellular Membranes--drug effects
Membrane Proteins--isolation & purification
Mitochondria, Liver--drug effects
Mitochondrial Swelling--drug effects
Models, Biological
Oxidative Stress
Oxygen--metabolism
Permeability--drug effects
Peroxides--pharmacology
Phenanthrolines--pharmacology
Rats
Rats, Wistar
Reactive Oxygen Species--metabolism
tert-Butylhydroperoxide