The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation.

Clark, G J

The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation. [electronic resource] - The Journal of biological chemistry Apr 1997 - 10608-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.272.16.10608 doi


3T3 Cells
Amino Acid Sequence
Animals
Cell Division
Cell Transformation, Neoplastic
DNA, Complementary
Fetus
GTP-Binding Proteins--biosynthesis
Gene Library
Genes, ras
Growth Substances--metabolism
Kinetics
Liver--metabolism
Mice
Molecular Sequence Data
Monomeric GTP-Binding Proteins
Neuropeptides--biosynthesis
Oocytes--physiology
Protein Prenylation
Ras Homolog Enriched in Brain Protein
Rats
Recombinant Fusion Proteins--biosynthesis
Sequence Homology, Amino Acid
Signal Transduction
Transcriptional Activation
Transfection
Xenopus laevis
ras Proteins--chemistry