Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers.

Crosbie, S J

Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers. [electronic resource] - Human & experimental toxicology Mar 1997 - 131-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0960-3271

10.1177/096032719701600301 doi


Animals
Aryl Hydrocarbon Hydroxylases
Brain--drug effects
Cell Line
Corn Oil--pharmacology
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP2E1--biosynthesis
Cytochrome P-450 CYP2E1 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction--drug effects
Enzyme Inhibitors--pharmacology
Ethanol--pharmacology
Hexanes--metabolism
Hexanols--metabolism
Humans
Liver--drug effects
Lung--drug effects
Male
Metyrapone--pharmacology
Microsomes--drug effects
Microsomes, Liver--drug effects
Muscle, Skeletal--drug effects
Oxidoreductases, N-Demethylating--antagonists & inhibitors
Phenobarbital--pharmacology
Random Allocation
Rats
Rats, Wistar
beta-Naphthoflavone--pharmacology