A nonradioisotope approach to study the in vivo metabolism of phosphorothioate oligonucleotides.

Cohen, A S

A nonradioisotope approach to study the in vivo metabolism of phosphorothioate oligonucleotides. [electronic resource] - Antisense & nucleic acid drug development Feb 1997 - 13-22 p. digital

Publication Type: Journal Article

1087-2906

10.1089/oli.1.1997.7.13 doi


Animals
Drug Administration Schedule
Genes, gag--drug effects
HIV-1--genetics
Humans
Injections, Intravenous
Macaca mulatta
Oligodeoxyribonucleotides, Antisense
Oligonucleotides, Antisense--administration & dosage
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization--methods
Thionucleotides--administration & dosage