A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation.

Oliver, C F

A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation. [electronic resource] - Biochemistry Feb 1997 - 1567-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2960

10.1021/bi962826c doi


Bacillus megaterium--chemistry
Bacterial Proteins
Catalysis
Cytochrome P-450 Enzyme System--chemistry
Hydroxylation
Magnetic Resonance Spectroscopy
Mixed Function Oxygenases--chemistry
Mutagenesis
NADPH-Ferrihemoprotein Reductase
Substrate Specificity