Differential efficacy of lymphocyte- and monocyte-selective pretreatment with a type 4 phosphodiesterase inhibitor on antigen-driven proliferation and cytokine gene expression.

Essayan, D M

Differential efficacy of lymphocyte- and monocyte-selective pretreatment with a type 4 phosphodiesterase inhibitor on antigen-driven proliferation and cytokine gene expression. [electronic resource] - The Journal of allergy and clinical immunology Jan 1997 - 28-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0091-6749

10.1016/s0091-6749(97)70297-5 doi


3',5'-Cyclic-AMP Phosphodiesterases
Allergens--pharmacology
Antigens--pharmacology
Cells, Cultured
Cyclic AMP--metabolism
Cyclic Nucleotide Phosphodiesterases, Type 4
Cytokines--biosynthesis
Gene Expression--drug effects
Humans
Leukocytes, Mononuclear--drug effects
Lymphocyte Activation--drug effects
Lymphocytes--drug effects
Phosphodiesterase Inhibitors--pharmacology
Phosphoric Diester Hydrolases--drug effects
Plant Proteins--pharmacology
Pyrrolidinones--pharmacology
Receptors, Cell Surface--metabolism
Rolipram
Tetanus Toxoid--pharmacology