Antagonists of the mannose receptor and the LDL receptor-related protein dramatically delay the clearance of tissue plasminogen activator.

Biessen, E A

Antagonists of the mannose receptor and the LDL receptor-related protein dramatically delay the clearance of tissue plasminogen activator. [electronic resource] - Circulation Jan 1997 - 46-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-7322

10.1161/01.cir.95.1.46 doi


Animals
Carrier Proteins--pharmacology
Cells, Cultured
Endocytosis--drug effects
Glutathione Transferase--pharmacology
Half-Life
Humans
Lectins, C-Type
Liver--metabolism
Low Density Lipoprotein Receptor-Related Protein-1
Mannose Receptor
Mannose-Binding Lectins
Mannosides--pharmacology
Oligopeptides--pharmacology
Rats
Rats, Wistar
Receptors, Cell Surface--antagonists & inhibitors
Receptors, Immunologic--antagonists & inhibitors
Receptors, LDL--antagonists & inhibitors
Recombinant Fusion Proteins--pharmacology
Tissue Plasminogen Activator--pharmacokinetics