Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential.

Huang, S

Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential. [electronic resource] - Oncogene Dec 1996 - 2339-47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0950-9232


Animals
Apoptosis
Humans
Lung Neoplasms--secondary
Male
Melanoma--genetics
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Proteins--genetics
Neoplasm Transplantation
Phenotype
Proto-Oncogene Mas
Proto-Oncogene Proteins c-kit--genetics
RNA, Messenger--metabolism
Skin Neoplasms--genetics
Stem Cell Factor--metabolism
Transfection
Tumor Cells, Cultured