Decreased methylene tetrahydrofolate reductase activity due to the 677C-->T mutation in families with spina bifida offspring.

van der Put, N M

Decreased methylene tetrahydrofolate reductase activity due to the 677C-->T mutation in families with spina bifida offspring. [electronic resource] - Journal of molecular medicine (Berlin, Germany) Nov 1996 - 691-4 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0946-2716

10.1007/s001090050073 doi


5,10-Methylenetetrahydrofolate Reductase (FADH2)
Adult
Aged
Child
Cysteine--blood
Female
Folic Acid--blood
Genetic Linkage
Genotype
Homocysteine--blood
Homozygote
Humans
Lod Score
Lymphocytes--enzymology
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Netherlands
Oxidoreductases--deficiency
Point Mutation--genetics
Risk Factors
Spinal Dysraphism--epidemiology
Vitamin B 12--blood